Caroline Lea-Carnall
I am a theoretical neuroscientist with a specific interest in the neurochemical mechanisms that underlie plasticity. I use a combination of computational and neuroimaging methods to study plasticity in humans in vivo.
I am a theoretical neuroscientist with a specific interest in the neurochemical mechanisms that underlie plasticity. I use a combination of computational and neuroimaging methods to study plasticity in humans in vivo.
I did my general medical training at Grant Medical College, Mumbai India beofre training in general psychiatry at Oxford & Leeds. I moved to Manchester in 2008 to specialise in Child & Adolescent Psychiatry. I was awarded a research training fellowship by NIHR Bioedical Research centre in 2011-12 to study the behavioural phenotype of Neurofibromatosis type 1 (NF1). My PhD thesis described for the first time, a high prevalence of Autism Spectrum Disorders (ASD) in NF1. This work has formed the basis for my research programme in NF1 autism. In August 2018 I was awarded the Francis Collins Scholarship in NF1 by NTAP (Neurofibromatosis Therapeutics Acceleration Program), at John’s Hopkins University (http://www.n-tap.org/new-research-tools-for-neurofibromatosis-type-1-2-2-2/). This work will allow me to investigate the use of non-invasive brain stimulation for working memory deficits in NF1.
I am a PhD student in computational neuroscience with a background in engineering and theoretical physics. My research includes providing mathematical framework to optimise the parameters of non-invasive brain stimulations with the purpose of improving Working Memory.
More specifically, I am interested in bridging between empirical data and computational models of large-scale brain networks by drawing implications from latent manifold of neuroimaging data. With insights from dynamical systems and complex system physics, I seek to put constraints on computational models of brain networks using the embedding and intrinsic dimension of Working Memory manifold.