New Paper: A mean-field model of glutamate and GABA synaptic dynamics for functional MRS

In our latest paper we test the hypothesis that fMRS detects shifts in metabolite concentrations as they move from presynaptic vesicles, where they are largely invisible to MRS, to extracellular and cytosolic pools, where they are visible to MRS using a mean field model which links the neural dynamics of neurotransmitters at the microscopic-level to the macroscopic-level imaging measurements obtained in experimental studies.

A mean-field model of glutamate and GABA synaptic dynamics for functional MRS Lea-Carnall CA, El-Deredy W, Stagg CJ, Williams SR, Trujillo-Barreto NJ, NeuroImage, DOI: 10.1016/j.neuroimage.2022.119813